PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8674115-3 1996 This exonuclease activity is intrinsic to the wild-type p53 protein: it copurified with p53 during p53 preparation; only purified wild-type p53, but not identically purified mutant p53 proteins displayed exonuclease activity; the exonuclease activity could be reconstituted from SDS gel-purified and urea-renatured p53 protein and mapped to the core domain of the p53 molecule; and finally, purified p53 protein could be UV-cross-linked to GMP. guanosine 5'-monophosphorothioate 440-443 tumor protein p53 Homo sapiens 56-59 33742136-7 2021 SNORD50A/B deletion in p53 wild-type breast cancer cells will release GMPS and induce the translocation of GMPS into the nucleus, where GMPS can recruit USP7 and form a complex with p53, thereby decreasing p53 ubiquitination, stabilizing p53 proteins, and inhibiting malignant phenotypes of cancer cells. guanosine 5'-monophosphorothioate 70-74 tumor protein p53 Homo sapiens 23-26 21673677-3 2011 RESULTS: Presence of GMP (21% of the cases) was significantly associated with high-grade tumours and TP53 mutations in addition to the basal-like and HER2 subtypes of breast cancer as defined by gene expression data. guanosine 5'-monophosphorothioate 21-24 tumor protein p53 Homo sapiens 101-105