PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31594538-4 2019 RESULTS: Here, we present data suggesting that LSH regulates p53 in cis through two pathways: prevention proteasomal degradation through its deubiquitination, which is achieved by reducing the lysine 11-linked, lysine 48-linked polyubiquitin chains (K11 and K48) on p53; and revival of the transcriptional activity of p53 by forming a complex with PKM2 (pyruvate kinase 2). Pyruvates 354-362 helicase, lymphoid specific Homo sapiens 47-50