PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19356113-0	2009	Utility of Nicotiana tabacum cell suspension cultures expressing human CYP1A1, CYP1A2 and CYP3A4 to study the oxidative metabolism of the herbicide 14C-fluometuron.	Carbon-14	148-151	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	79-85	
33995046-11	2021	The formation of 14C-adducts due to 14C-8-MOP-derived radioactivity bound to HLMs confirmed the irreversible inhibition of CYP1A2 activity.	Carbon-14	17-20	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	123-129	
19356113-1	2009	The metabolism and biotransformation of the (14)C-labeled phenylurea herbicide fluometuron was examined using tobacco cell suspension cultures transformed separately with human cyp1a1, cyp1a2 and cyp3a4, and corresponding non-transformed cultures in order to screen and predict metabolic patterns.	Carbon-14	44-49	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	185-191	
17193320-0	2006	Comparison of the biotransformation of the 14C-labelled insecticide carbaryl by non-transformed and human CYP1A1-, CYP1A2-, and CYP3A4-transgenic cell cultures of Nicotiana tabacum.	Carbon-14	43-46	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	115-121	
17193320-1	2006	Transgenic tobacco-cell-suspension cultures expressing separately the human cytochrome P450 monooxygenases CYP1A1, CYP1A2, and CYP3A4 were utilized to study the biotransformation of the 14C-labelled insecticide carbaryl (=naphthalen-1-yl methylcarbamate).	Carbon-14	186-189	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	115-121	
16484082-1	2006	In the present investigation, the oxidative metabolism of 14C-labeled metamitron was examined in plant cell cultures of tobacco overexpressing human P450 enzymes CYP1A1 or CYP1A2; special interest was in the aromatic hydroxylation of the herbicide.	Carbon-14	58-61	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	172-178	
12852754-7	2003	Combination of both structural features provided 14c (p38: 0.34 microM, inhibition of CYP1A2 0%, 2C9 2.6%, 2C19 7.6% at 10 microM), which was selected for further development.	Carbon-14	49-52	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	86-92	
16402549-4	2005	Portions of the primary metabolites were 29.3% (NT culture), 34.3% (CYP1A1 culture), and 50.7% of applied 14C (CYP1A2 culture).	Carbon-14	106-109	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	111-117	
8591723-3	1995	The cell lines that expressed CYP1A1, CYP1A2, and CYP2D6 were shown to be capable of metabolizing [14C]ondansetron.	Carbon-14	99-102	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	38-44	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	54-58	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-6	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	54-58	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	177-183	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	54-57	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-6	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	54-57	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	177-183	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	75-78	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-6	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	75-78	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	177-183	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	75-78	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-6	
9435160-3	1998	CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP3A4 converted [14C]linoleic acid to 14C-labeled 11-hydroxyoctadecadienoic acid (11-HODE), whereas [14C]arachidonic acid was oxygenated by CYP1A2 and CYP3A4 to 14C-labeled 13-hydroxyeicosatrienoic acid (13-HETE), 10-HETE and 7-HETE as determined by HPLC.	Carbon-14	75-78	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	177-183