PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29719619-4 2018 TP-064 inhibited the methyltransferase activity of PRMT4 with high potency (half-maximal inhibitory concentration, IC50 < 10 nM) and selectivity over other PRMT family proteins, and reduced arginine dimethylation of the PRMT4 substrates BRG1-associated factor 155 (BAF155; IC50= 340 +- 30 nM) and Mediator complex subunit 12 (MED12; IC50 = 43 +- 10 nM). TP-064 0-6 mediator complex subunit 12 Homo sapiens 300-327 29719619-4 2018 TP-064 inhibited the methyltransferase activity of PRMT4 with high potency (half-maximal inhibitory concentration, IC50 < 10 nM) and selectivity over other PRMT family proteins, and reduced arginine dimethylation of the PRMT4 substrates BRG1-associated factor 155 (BAF155; IC50= 340 +- 30 nM) and Mediator complex subunit 12 (MED12; IC50 = 43 +- 10 nM). TP-064 0-6 mediator complex subunit 12 Homo sapiens 329-334