PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20641992-1 2004 These phosphonates tend to accumulate in osteoclasts at areas of increased bone metabolism by inhibiting the farnesyl diphosphate synthase, an important enzyme of the mevalonate pathway in the cell (1), as described by Drake et. Organophosphonates 6-18 farnesyl diphosphate synthetase Mus musculus 109-138