PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8106004-0 1993 Antidepressant/anxiolytic ipsapirone inhibits cold-induced hypothalamic TRH release. ipsapirone 26-36 thyrotropin releasing hormone Homo sapiens 72-75 8106004-2 1993 Therefore, the aim of the present study was to evaluate, by means of a push-pull cannula implanted in the median eminence (ME), whether ipsapirone acts primarily through an inhibition of cold-elicited thyrotropin-releasing hormone (TRH) release. ipsapirone 136-146 thyrotropin releasing hormone Homo sapiens 201-230 8106004-3 1993 Ipsapirone administration (10 mg kg-1 i.p., 30 min before cold) prevented cold-elicited TRH release, thereby confirming the above hypothesis. ipsapirone 0-10 thyrotropin releasing hormone Homo sapiens 88-91