PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22645123-4 2012 We showed that our BET (Bromodomain and Extra-Terminal domain)-specific bromodomain inhibitor MS417, designed to block BRD4 binding to the acetylated NF-kappaB, effectively attenuates NF-kappaB transcriptional activation of proinflammatory genes in kidney cells treated with TNFalpha or infected by HIV. MS417 94-99 nuclear factor kappa B subunit 1 Homo sapiens 150-159 22645123-4 2012 We showed that our BET (Bromodomain and Extra-Terminal domain)-specific bromodomain inhibitor MS417, designed to block BRD4 binding to the acetylated NF-kappaB, effectively attenuates NF-kappaB transcriptional activation of proinflammatory genes in kidney cells treated with TNFalpha or infected by HIV. MS417 94-99 nuclear factor kappa B subunit 1 Homo sapiens 184-193