PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24824895-5 2014 Herein, we present results of culturing of human DM1 myoblasts and fibroblasts with two small-molecule ATP-binding site-specific kinase inhibitors, C16 and C51, which resulted in the alleviation of the dominant-negative effects of CUG repeat expansion. 3-Carboxyumbelliferyl beta-D-galactopyranoside 231-234 DM1 protein kinase Homo sapiens 49-52 20690904-3 2010 The presence of an expanded CUG trinucleotide repeat in the 3"-UTR (3"-untranslated region) of the DMPK (myotonic dystrophy protein kinase) gene causes the attraction of RNA-binding proteins by the nuclear-located mutant transcripts. 3-Carboxyumbelliferyl beta-D-galactopyranoside 28-31 DM1 protein kinase Homo sapiens 99-103 20690904-3 2010 The presence of an expanded CUG trinucleotide repeat in the 3"-UTR (3"-untranslated region) of the DMPK (myotonic dystrophy protein kinase) gene causes the attraction of RNA-binding proteins by the nuclear-located mutant transcripts. 3-Carboxyumbelliferyl beta-D-galactopyranoside 28-31 DM1 protein kinase Homo sapiens 105-138 11686919-3 2001 RNA trans-dominant models, which hypothesize that the expanded CUG trinucleotide repeat on DMPK mRNA sequesters a factor or disrupts the RNA metabolism of the DMPK mRNA itself and other mRNAs in a trans dominant manner, have been proposed. 3-Carboxyumbelliferyl beta-D-galactopyranoside 63-66 DM1 protein kinase Homo sapiens 91-95 20502647-2 2010 The DMPK transcripts containing expanded CUG repeats accumulate in nuclear foci and ultimately cause mis-splicing of secondary genes through the dysregulation of RNA-binding proteins including Muscleblind 1 (MBNL1) and CUG binding protein 1 (CUGBP1). 3-Carboxyumbelliferyl beta-D-galactopyranoside 41-44 DM1 protein kinase Homo sapiens 4-8 11686919-3 2001 RNA trans-dominant models, which hypothesize that the expanded CUG trinucleotide repeat on DMPK mRNA sequesters a factor or disrupts the RNA metabolism of the DMPK mRNA itself and other mRNAs in a trans dominant manner, have been proposed. 3-Carboxyumbelliferyl beta-D-galactopyranoside 63-66 DM1 protein kinase Homo sapiens 159-163