PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23933069-2 2013 To uncover the details of Gbx functions, we first examined the dose dependency of its effects on brain formation in zebrafish and found that high-dose gbx2 mRNA injection affected the entire forebrain and midbrain, whereas low-dose mRNA specifically disrupted the isthmic folding at the midbrain-hindbrain boundary (MHB) but only weakly affected the expression of genes involved in MHB specification. GBX 26-29 gastrulation brain homeobox 2 Danio rerio 151-155