PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25975640-4 2015 A series of WZ4002 analogs, derived from anilinopyrimidine and 3-substituted-2-cyanoacrylamide scaffolds, exhibit strong and selective inhibitory activity against clinically relevant EGFR(L858R) and EGFR(L858R/T790M). N-phenylpyrimidin-2-amine 41-58 epidermal growth factor receptor Homo sapiens 183-187 34636023-7 2021 Substructures such as anilinopyrimidine, acrylamide, amino phenyl, methoxy phenyl, and thienopyrimidinyl amide appeared more in highly active inhibitors against double-mutant EGFR. N-phenylpyrimidin-2-amine 22-39 epidermal growth factor receptor Homo sapiens 175-179 23668441-0 2013 Novel hybrids of (phenylsulfonyl)furoxan and anilinopyrimidine as potent and selective epidermal growth factor receptor inhibitors for intervention of non-small-cell lung cancer. N-phenylpyrimidin-2-amine 45-62 epidermal growth factor receptor Homo sapiens 87-119 23668441-1 2013 A series of hybrids (12a-k) from (phenylsulfonyl)furoxan and anilinopyrimidine were synthesized and biologically evaluated as epidermal growth factor receptor (EGFR) inhibitors for intervention of non-small-cell lung cancer (NSCLC). N-phenylpyrimidin-2-amine 61-78 epidermal growth factor receptor Homo sapiens 126-158 23668441-1 2013 A series of hybrids (12a-k) from (phenylsulfonyl)furoxan and anilinopyrimidine were synthesized and biologically evaluated as epidermal growth factor receptor (EGFR) inhibitors for intervention of non-small-cell lung cancer (NSCLC). N-phenylpyrimidin-2-amine 61-78 epidermal growth factor receptor Homo sapiens 160-164 10639288-3 1999 Several elaborations of the fundamental anilinopyrimidine pharmacophore have been reported as potent and selective inhibitors of the epidermal growth factor receptor (EGFr) tyrosine kinase. N-phenylpyrimidin-2-amine 40-57 epidermal growth factor receptor Homo sapiens 167-171 29250520-0 2017 Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors. N-phenylpyrimidin-2-amine 53-70 epidermal growth factor receptor Homo sapiens 86-90