PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31923631-2	2020	The dihydroquinazoline derivatives were rationally designed by modifying the amide group and relocating the alpha -hydrophobic substituent on the hairpin turn side chain of lead compound 2 to the C4-position on the 3,4-dihydroquinazoline scaffold to facilitate interactions with the S1, S2 and S1" subsites of BACE-1.	3,4-Dihydroquinazoline	215-237	beta-secretase 1	Homo sapiens	310-316