PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15130612-8	2004	Early-passage cells showed dose-responsive caspase-3 activation following exposure to sodium arsenite, whereas caspase-3 activation of late-passage cells dropped to background levels at toxicant dosages above 50 ppb.	sodium arsenite	86-101	caspase 3	Mus musculus	43-52	
35351881-7	2022	Western blotting showed increased levels of cleaved PARP-1 and cleaved caspase-3 in SA-treated mice consistent with SA-induced apoptosis.	sodium arsenite	84-86	caspase 3	Mus musculus	71-80	
10652248-2	2000	Previously, we showed that the cell death induced in day 9 mouse embryos by three teratogens, hyperthermia (HS), 4-hydroperoxycyclophosphamide (4-CP), and sodium arsenite (As), is apoptotic in nature involving the activation of caspase-3, cleavage of poly(ADP-ribose) polymerase (PARP), and DNA fragmentation.	sodium arsenite	155-170	caspase 3	Mus musculus	228-237	
10200514-3	1998	We show that three teratogens, hyperthermia, cyclophosphamide and sodium arsenite induce an increase in cell death in day 9.0 mouse embryos with concurrent induction of DNA fragmentation, activation of caspase-3 and the cleavage of poly (ADP-ribose) polymerase (PARP).	sodium arsenite	66-81	caspase 3	Mus musculus	202-211	
35351881-7	2022	Western blotting showed increased levels of cleaved PARP-1 and cleaved caspase-3 in SA-treated mice consistent with SA-induced apoptosis.	sodium arsenite	116-118	caspase 3	Mus musculus	71-80	
32519758-7	2020	NaAsO2 exposure was associated with marked increases in renal inflammatory marker (interleukin-1beta and tumor necrosis factor-alpha) and apoptosis indicators including Bax and caspase-3 levels contaminant with a marked decrease in Bcl-2, an anti-apoptotic protein, in the NaAsO2- treated group compared with the control group.	sodium arsenite	0-6	caspase 3	Mus musculus	177-186	
33242462-7	2021	Immunohistochemical analysis of testis sections of NaAsO2-treated mice showed high caspase-3 expression.	sodium arsenite	51-57	caspase 3	Mus musculus	83-92