PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27129674-7	2016	Whereas, low doses of sodium arsenite cause Nrf2 and HO-1 activation and increased CREB phosphorylation in the hippocampus.	sodium arsenite	22-37	heme oxygenase 1	Rattus norvegicus	53-57	
2912370-4	1989	Using radioimmunoassay, it was shown that other agents known to increase the testicular heme oxygenase, sodium arsenate and sodium arsenite, also increased the microsomal content of HO-1.	sodium arsenite	124-139	heme oxygenase 1	Rattus norvegicus	182-186	
28726208-3	2017	Heme oxygenase 1, an inducible form of the enzyme, is normally not expressed in the cerebral vessels, but the enzyme is expressed in response to sodium metaarsenite.	sodium arsenite	145-164	heme oxygenase 1	Rattus norvegicus	0-16	
27129674-9	2016	Moreover, it seems that the neuroprotective effects of ultra-low concentrations of sodium arsenite on Abeta-induced memory impairment is mediated via an increase Nrf2, HO-1 and CREB phosphorylation levels and decrease caspase-3 and NF-kappaB amount.	sodium arsenite	83-98	heme oxygenase 1	Rattus norvegicus	168-172	
9837857-1	1998	Heme oxygenase 1 (HO-1), a stress response protein, is highly induced in response to various agents causing oxidative stress including ultraviolet irradiation, sodium arsenite, hyperoxia, and glutathione depletors.	sodium arsenite	160-175	heme oxygenase 1	Rattus norvegicus	0-16	
23603382-8	2013	The expressions of HSP70 and HO-1 were significantly (P<0.05) increased in the NaAsO2 group and reduced in the combined treatment group.	sodium arsenite	82-88	heme oxygenase 1	Rattus norvegicus	29-33	
12637567-1	2003	Heme oxygenase-1 (HO-1) gene expression is induced by various oxidative stress stimuli including sodium arsenite.	sodium arsenite	97-112	heme oxygenase 1	Rattus norvegicus	0-22	
12637567-3	2003	The Jun N-terminal kinase (JNK) inhibitor SP600125 decreased sodium arsenite-mediated induction of HO-1 mRNA expression.	sodium arsenite	61-76	heme oxygenase 1	Rattus norvegicus	99-103	
9837857-1	1998	Heme oxygenase 1 (HO-1), a stress response protein, is highly induced in response to various agents causing oxidative stress including ultraviolet irradiation, sodium arsenite, hyperoxia, and glutathione depletors.	sodium arsenite	160-175	heme oxygenase 1	Rattus norvegicus	18-22	
7729015-4	1995	Treatment of RASMCs with hemin and sodium arsenite, which are inducers of HO-1, stimulated RASMC cGMP without stimulating nitrite release or inducible NO synthase expression, and the induced elevations of cGMP were not inhibited by the NO synthase inhibitor NG-methyl-L-arginine.	sodium arsenite	35-50	heme oxygenase 1	Rattus norvegicus	74-78