PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17070520-0 2006 Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. sodium arsenite 0-15 CASP8 and FADD like apoptosis regulator Homo sapiens 144-149 17070520-7 2006 Furthermore, activation of cJun and suppression of NF-kappaB by sodium arsenite resulted in upregulation of the endogenous TRAIL and downregulation of the cFLIP gene expression (which encodes one of the main anti-apoptotic proteins in melanomas) followed by cFLIP protein degradation and, finally, by acceleration of TRAIL-induced apoptosis. sodium arsenite 64-79 CASP8 and FADD like apoptosis regulator Homo sapiens 155-160 17070520-7 2006 Furthermore, activation of cJun and suppression of NF-kappaB by sodium arsenite resulted in upregulation of the endogenous TRAIL and downregulation of the cFLIP gene expression (which encodes one of the main anti-apoptotic proteins in melanomas) followed by cFLIP protein degradation and, finally, by acceleration of TRAIL-induced apoptosis. sodium arsenite 64-79 CASP8 and FADD like apoptosis regulator Homo sapiens 258-263