PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16497974-6 2006 Sodium arsenite was shown to down-regulate the expression of survivin at both the protein and RNA levels in a time- and dose-dependent manner, thus inhibiting cell growth, inducing apoptosis, and enhancing the caspase-3 activity in ATL cells. sodium arsenite 0-15 caspase 3 Homo sapiens 210-219 20188806-3 2010 The results showed that folate deficiency significantly aggravated the NaAsO(2)-induced apoptotic progression [evidenced by phosphatidylserine externalization, cleavage of caspase-3 and poly (ADP-ribose) polymerase (PARP), collapse of mitochondrial potential, and release of cytochrome c from the mitochondria] and decrease of cell viability. sodium arsenite 71-79 caspase 3 Homo sapiens 172-214 19536524-3 2009 NaAsO2 treatment (0-30 microM) was also found to induce phosphatidylserine externalization, a hallmark of apoptosis; to disrupt the mitochondrial membrane potential (Deltapsi ( m )); to cause the release of cytochrome c into the cytosol, and to trigger cleavage of caspase-3 and poly (ADP-ribose) polymerase (PARP) in a dose-dependent manner. sodium arsenite 0-6 caspase 3 Homo sapiens 265-307 35298964-9 2022 RESULTS: Compared with the control group, with the gradual increasing dose of NaAsO2, cell viability was considerable reduced, and increased rate of apoptosis, intracellular GSH level was decreased significantly, ROS was increased, mitochondrial structure was damaged, mitochondrial membrane potential DeltaPsim and Bcl2/BAX lowered, the expression of Caspase3 and cleaved-caspase3 were significantly increased, resulting in mitochondrial apoptosis. sodium arsenite 78-84 caspase 3 Homo sapiens 352-360 35298964-11 2022 When BSO increased the inhibitory effect of NaAsO2 on GCLC, Compared with NaAsO2 group, the DeltaPsim and protein of Bcl-2/BAX, caspase3 and cleaved-capsase3 were increased. sodium arsenite 44-50 caspase 3 Homo sapiens 128-136 35298964-11 2022 When BSO increased the inhibitory effect of NaAsO2 on GCLC, Compared with NaAsO2 group, the DeltaPsim and protein of Bcl-2/BAX, caspase3 and cleaved-capsase3 were increased. sodium arsenite 74-80 caspase 3 Homo sapiens 128-136 31587475-7 2020 In addition, SA provoked the apoptosis by expanding the p53 and Bax levels, terminal deoxynucleotidyl transferase dUTP nick end labeling, and expression of caspase-3. sodium arsenite 13-15 caspase 3 Homo sapiens 156-165