PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24585092-9	2014	Importantly, their protective effects against insults from both sodium arsenite and H2O2 were Nrf2-dependent.	sodium arsenite	64-79	NFE2 like bZIP transcription factor 2	Homo sapiens	94-98	
25344162-9	2014	We found that the protein expression levels of Nrf2 were increased in both NaAsO2- and As2O3-treated cells.	sodium arsenite	75-81	NFE2 like bZIP transcription factor 2	Homo sapiens	47-51	
21861350-2	2011	METHODS: Chang hepatocytes were treated with 5, 10, 25 and 50 micromol/L of sodium arsenite (NaAsO2) for 6h, and RT-PCR were then performed to detect the mRNA expression of Nrf2, NQO1 and HO-1.	sodium arsenite	76-91	NFE2 like bZIP transcription factor 2	Homo sapiens	173-177	
21809430-3	2013	This study was conducted to evaluate the hepato-cellular Nrf2 and Nrf2-regulated antioxidant reactions of sodium arsenite exposure in Chang human hepatocytes.	sodium arsenite	106-121	NFE2 like bZIP transcription factor 2	Homo sapiens	57-61	
21809430-3	2013	This study was conducted to evaluate the hepato-cellular Nrf2 and Nrf2-regulated antioxidant reactions of sodium arsenite exposure in Chang human hepatocytes.	sodium arsenite	106-121	NFE2 like bZIP transcription factor 2	Homo sapiens	66-70	
21861350-3	2011	RESULTS: When exposed to 5, 10, 25 and 50 micromol/L of NaAsO2, Nrf2 mRNA were (100.74 +/- 3.70)%, (105.96 +/- 1.75)%, (101.76 +/- 1.01)% and (101.81 +/- 6.33)% of control,showing no statistic significance (P > 0.05).	sodium arsenite	56-62	NFE2 like bZIP transcription factor 2	Homo sapiens	64-68	
21643505-5	2011	While ten of the metals tested (cadmium, cobalt, copper, gold, iron, lead, mercury, silver, sodium arsenite and zinc) stimulated Nrf2-dependent transcriptional activity in at least three of the engineered cell lines, only three (cadmium, copper and sodium arsenite) were active in all five cell lines.	sodium arsenite	92-107	NFE2 like bZIP transcription factor 2	Homo sapiens	129-133	
21643505-5	2011	While ten of the metals tested (cadmium, cobalt, copper, gold, iron, lead, mercury, silver, sodium arsenite and zinc) stimulated Nrf2-dependent transcriptional activity in at least three of the engineered cell lines, only three (cadmium, copper and sodium arsenite) were active in all five cell lines.	sodium arsenite	249-264	NFE2 like bZIP transcription factor 2	Homo sapiens	129-133	
18417180-3	2008	Previously, we reported that activation of the Nrf2-mediated cellular defense pathway confers protection against toxic effects induced by sodium arsenite [As(III)] or monomethylarsonous acid [MMA(III)].	sodium arsenite	138-153	NFE2 like bZIP transcription factor 2	Homo sapiens	47-51	
14567983-4	2003	Thus, the effect of inorganic arsenic (as sodium arsenite) on Nrf2 expression and localization was studied in HaCaT cells, an immortalized human keratinocyte cell line.	sodium arsenite	42-57	NFE2 like bZIP transcription factor 2	Homo sapiens	62-66	
35624898-5	2022	This review focuses on the mechanisms regulating the mitochondrial formation of ROS after exposure to low concentrations of a specific arsenic compound, NaAsO2, and their crosstalk with the nuclear factor (erythroid-2 related) factor 2 antioxidant signaling and the endoplasmic reticulum stress response.	sodium arsenite	153-159	NFE2 like bZIP transcription factor 2	Homo sapiens	190-235	
31766100-6	2020	It alleviated sodium arsenite [As(III)]-induced intracellular oxidative stress in an Nrf2-dependent manner.	sodium arsenite	14-29	NFE2 like bZIP transcription factor 2	Homo sapiens	85-89	
30773942-5	2019	Moreover, NOR protected human lung epithelial Beas-2B cells against sodium arsenite [As(III)]-induced cytotoxicity in an Nrf2-dependent manner.	sodium arsenite	68-83	NFE2 like bZIP transcription factor 2	Homo sapiens	121-125	
31139082-9	2019	In addition, the effects of Pts on NaAsO2-induced cell viability were largely weakened when Nrf2 was knocked down.	sodium arsenite	35-41	NFE2 like bZIP transcription factor 2	Homo sapiens	92-96	
30227999-6	2018	Further studies indicated that 7-MBA activated Nrf2 signaling pathway and protected human lung epithelial Beas-2B cells against sodium arsenite [As(III)]-induced cytotoxicity in an Nrf2-dependent manner.	sodium arsenite	128-143	NFE2 like bZIP transcription factor 2	Homo sapiens	181-185	
28229933-5	2017	We investigated the activation of nuclear factor-E2-related factor 2 (Nrf2) which regulates various antioxidant genes including heme oxygenase-1 (HMOX1), following exposure to sodium arsenite or cadmium chloride in lamin knockdown human cell lines and primary HGPS human fibroblasts.	sodium arsenite	176-191	NFE2 like bZIP transcription factor 2	Homo sapiens	70-74	
29029432-0	2017	The involvement of Nrf2 in the protective effects of (-)-Epigallocatechin-3-gallate (EGCG) on NaAsO2-induced hepatotoxicity.	sodium arsenite	94-100	NFE2 like bZIP transcription factor 2	Homo sapiens	19-23	
27459794-3	2016	Western blot was used to evaluate the expression of Nrf2, quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (10-1) during sodium arsenite-induced transformation of HBE cells.	sodium arsenite	125-140	NFE2 like bZIP transcription factor 2	Homo sapiens	52-56	
27459794-7	2016	CONCLUSION: The transformation of HBE cells induced by chronic exposure to sodium arsenite is mediated by decreased Nrf2 level and its downstream NQO1 and HO-1 protein, which subsequently promote the malignant proliferation.	sodium arsenite	75-90	NFE2 like bZIP transcription factor 2	Homo sapiens	116-120