PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16424148-7	2006	Inhibition of MMP-2 by phenantroline and degradation of ADP by APT102, respectively, resulted in inhibition of TCIPA.	1,10-phenanthroline	23-36	matrix metallopeptidase 2	Homo sapiens	14-19	
11956628-4	2002	We investigated whether expression of MMP-2 and MMP-9 is associated with invasion ability of seven cervical cancer cells by administration of o-phenanthroline as MMP inhibitor.	1,10-phenanthroline	142-158	matrix metallopeptidase 2	Homo sapiens	38-43	
14732714-10	2004	(M392L)MMP-2 and (M392S)MMP-2 were inhibited by tissue inhibitor of metalloproteinases (TIMP)-1, -2, and -4 and by the zinc chelators 1,10-phenanthroline and a synthetic hydroxamate inhibitor, Batimastat, similar to the wild-type protein, indicating an unaltered active site topography.	1,10-phenanthroline	134-153	matrix metallopeptidase 2	Homo sapiens	7-12	
14732714-10	2004	(M392L)MMP-2 and (M392S)MMP-2 were inhibited by tissue inhibitor of metalloproteinases (TIMP)-1, -2, and -4 and by the zinc chelators 1,10-phenanthroline and a synthetic hydroxamate inhibitor, Batimastat, similar to the wild-type protein, indicating an unaltered active site topography.	1,10-phenanthroline	134-153	matrix metallopeptidase 2	Homo sapiens	24-29	
11426881-7	2001	Inhibition of MMP-2 and MMP-9 activities was partly prevented by the addition of 1,10 phenanthroline, a divalent metal chelator, to the amalgam conditioned buffers.	1,10-phenanthroline	81-100	matrix metallopeptidase 2	Homo sapiens	14-19	
11063876-4	2000	We found that an SDF-1 gradient increases the chemotaxis of BM and PB CD34(+) cells across Matrigel (BM > PB), which is blocked by inhibitors of MMPs (o-phenanthroline, rhTIMP-1, rhTIMP-2, and anti-MMP-9 and anti-MMP-2 antibodies) but enhanced by tumor necrosis factor-alpha (TNF-alpha), a strong stimulator of MMPs.	1,10-phenanthroline	154-170	matrix metallopeptidase 2	Homo sapiens	148-152	
10551322-8	1999	The release of MT1-MMP from the Con A-treated cells was inhibited by metalloproteinase inhibitors such as EDTA and o-phenanthroline, but not by MMP inhibitors including TIMP-1, TIMP-2 and BB94 or other proteinase inhibitors of serine, cysteine and aspartic proteinases.	1,10-phenanthroline	115-131	matrix metallopeptidase 2	Homo sapiens	19-22	
10708585-5	2000	Treatment of the T98G glioma spheroid with 1,10-phenanthroline, a specific inhibitor of MMPs, significantly inhibited not only the cell migration on the surface of the brain slice but also the invasion of the glioma cells into the slice.	1,10-phenanthroline	43-62	matrix metallopeptidase 2	Homo sapiens	88-92	
9699154-6	1998	This 66 kDa MMP was confirmed as gelatinase A (MMP-2) based on the results of its activity dependent on Ca2+ and inhibited in the presence of 1,10-phenanthroline or EDTA, as well as its specific immunoreactivity on the Western blot.	1,10-phenanthroline	142-161	matrix metallopeptidase 2	Homo sapiens	47-52	
10340464-5	1999	Upon treatment with chelating agents EDTA and 1,10-phenanthroline, the enzyme activities were inhibited indicating that those enzymes are likely matrix metalloproteinases (MMPs).	1,10-phenanthroline	46-65	matrix metallopeptidase 2	Homo sapiens	172-176	
8384126-2	1993	Like matrix metalloproteinases (MMPs), the enzyme was activated by trypsin and degraded type IV collagen and gelatin at a neutral pH, the activity was inhibited by EDTA and o-phenanthroline.	1,10-phenanthroline	173-189	matrix metallopeptidase 2	Homo sapiens	32-36	
8871536-3	1996	Treatment with 1,10-phenanthroline, a metalloprotease inhibitor, or with a synthetic dipeptide, containing a blocking sequence (ala-phe) specific for MMPs, resulted in a > 90% reduction in glioma invasion.	1,10-phenanthroline	15-34	matrix metallopeptidase 2	Homo sapiens	150-154	
24136115-8	2014	The MMP-2 platelet activation pathway can be synergistically inhibited with the non-selective MMP inhibitor, 1,10-phenanthroline, plus a JAK 2 inhibitor.	1,10-phenanthroline	109-128	matrix metallopeptidase 2	Homo sapiens	4-9