PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27318969-2	2016	This study further attempted to investigate the involvement of HCD-induced autophagy in brain tumor cell lines neuroblastoma N18 and glioma C6 through the induction of reactive oxygen species (ROS) and the activation of p38 and ERK-1/2 pathway.	20-hydroxycholesterol	63-66	mitogen-activated protein kinase 1	Homo sapiens	220-223	
27318969-5	2016	Additionally, HCD was found to significantly induce p-p38 MAPK and p-ERK-1/2 proteins by Western blot, which implies that HCD is a potential therapeutic anticancer agent that exerts its activity through inducing ROS-mediation for the autophagy of brain tumor cells.	20-hydroxycholesterol	14-17	mitogen-activated protein kinase 1	Homo sapiens	54-57	
31325047-0	2019	20(S)-hydroxycholesterol and simvastatin synergistically enhance osteogenic differentiation of marrow stromal cells and bone regeneration by initiation of Raf/MEK/ERK signaling.	20-hydroxycholesterol	0-24	mitogen-activated protein kinase 1	Homo sapiens	163-166	
27318969-5	2016	Additionally, HCD was found to significantly induce p-p38 MAPK and p-ERK-1/2 proteins by Western blot, which implies that HCD is a potential therapeutic anticancer agent that exerts its activity through inducing ROS-mediation for the autophagy of brain tumor cells.	20-hydroxycholesterol	14-17	mitogen-activated protein kinase 1	Homo sapiens	69-76