PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19129255-1 2009 We previously reported in ischemic acute kidney injury (AKI) in mice that caspase-1-mediated production of interleukin-18 (IL-18) is pathogenic and that macrophage depletion by liposome-encapsulated clodronate (LEC) is protective. 4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE 211-214 caspase 1 Mus musculus 74-83