PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22945510-9	2012	CONCLUSION: Lunasin inhibited alphaVbeta3 integrin-mediated proinflammatory markers and downregulated Akt-mediated NF-kappaB pathways through interaction with alphaVbeta3 integrin.	LUNASINE	12-19	AKT serine/threonine kinase 1	Homo sapiens	102-105	
29113347-7	2017	Taken together, our findings suggest that lunasin inhibits PCSK9 expression by down-regulating HNF-1alpha and enhances LDLR expression via PI3K/Akt-mediated activation of SREBP-2 pathway, thereby functionally enhances LDL uptake in HepG2 cells and in ApoE-/- mice.	LUNASINE	42-49	AKT serine/threonine kinase 1	Homo sapiens	144-147	
27175819-6	2016	Meanwhile, we also found that lunasin inhibited the phosphorylation of focal adhesion kinase (FAK), Src, Akt, ERK and nucleus translocation of NF-kappaB, which indicates that, possibly via competing with alphaVbeta3 or alphaVbeta5/alpha5beta1 integrin, lunasin suppresses the metastasis of breast cancer cells through integrin-mediated FAK/Akt/ERK and NF-kappaB signaling pathways followed by downregulation of the activity and expression of MMP-2/-9.	LUNASINE	30-37	AKT serine/threonine kinase 1	Homo sapiens	105-108	
27175819-6	2016	Meanwhile, we also found that lunasin inhibited the phosphorylation of focal adhesion kinase (FAK), Src, Akt, ERK and nucleus translocation of NF-kappaB, which indicates that, possibly via competing with alphaVbeta3 or alphaVbeta5/alpha5beta1 integrin, lunasin suppresses the metastasis of breast cancer cells through integrin-mediated FAK/Akt/ERK and NF-kappaB signaling pathways followed by downregulation of the activity and expression of MMP-2/-9.	LUNASINE	30-37	AKT serine/threonine kinase 1	Homo sapiens	340-343