PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29113347-7 2017 Taken together, our findings suggest that lunasin inhibits PCSK9 expression by down-regulating HNF-1alpha and enhances LDLR expression via PI3K/Akt-mediated activation of SREBP-2 pathway, thereby functionally enhances LDL uptake in HepG2 cells and in ApoE-/- mice. LUNASINE 42-49 low density lipoprotein receptor Homo sapiens 119-123