PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33767160-8 2021 In particular, the p38alpha kinase inhibitor ralimetinib, which has already entered clinical trials, promoted sensitization of patient-derived CRC-SCs to chemotherapeutic agents commonly used for CRC treatment and showed a synthetic lethality effect when used in combination with the MEK1 inhibitor trametinib. Ralimetinib 45-56 mitogen-activated protein kinase kinase 1 Homo sapiens 284-288