PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25862641-7 2015 In LPS-induced septic mice, both pretreatment and treatment with L48H37 significantly improved survival and protected lung injury. 1-ethyl-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]piperidin-4-one 65-71 toll-like receptor 4 Mus musculus 3-6 25862641-3 2015 Our previous studies have found that a curcumin analog, L48H37 [1-ethyl-3,5-bis(3,4,5-trimethoxybenzylidene)piperidin-4-one], was able to inhibit LPS-induced inflammation, particularly tumor necrosis factor alpha and interleukin 6 production and gene expression in mouse macrophages. 1-ethyl-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]piperidin-4-one 56-62 toll-like receptor 4 Mus musculus 146-149