PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33420377-8 2021 Mechanistically, we found that PFK158 downregulated the CBPt/Cis-induced upregulation of RAD51 expression and enhanced CBPt/Cis-induced DNA damage as demonstrated by an increase in gamma-H2AX levels in HEC-1B and ARK-2 cells, potentially revealing a means to enhance PFK158-induced chemosensitivity. PFK-158 31-37 RAD51 recombinase Homo sapiens 89-94