PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35144528-11	2022	The S1PR1 antagonist W146 alleviated NTG-induced hyperalgesia and suppressed the upregulation of CGRP, c-fos and pSTAT3 in the TCC.	W146	21-25	sphingosine-1-phosphate receptor 1	Mus musculus	4-9	
29260347-7	2018	Moreover, when apoM+/+ mice were treated with W146, a S1P receptor (S1PR1) antagonist, these inflammatory biomarkers could be significantly upregulated by LPS-induced ALI.	W146	46-50	sphingosine-1-phosphate receptor 1	Mus musculus	54-57	
30569161-9	2019	Furthermore, the mRNA expression levels of IL-1beta and MCP-1 were significantly elevated following addition of the S1PR1 inhibitor W146, but not by the scavenger receptor class B type I inhibitor, block lipid transport-1 (BLT-1), in apoMTg cells prior to TNF-alpha treatment.	W146	132-136	sphingosine-1-phosphate receptor 1	Mus musculus	116-121	
30359564-9	2019	S1P induced vasodilation in denuded aortic rings was blocked by W146 but caused no vasodilation in endothelium-intact rings.	W146	64-68	sphingosine-1-phosphate receptor 1	Mus musculus	0-3	
32290092-6	2020	Constitutive barrier stability of HUVEC, but not EA.hy926, was significantly compromised by the S1PR1 antagonist W146 and by the anti-S1P antibody Sphingomab.	W146	113-117	sphingosine-1-phosphate receptor 1	Mus musculus	96-101	
29260347-7	2018	Moreover, when apoM+/+ mice were treated with W146, a S1P receptor (S1PR1) antagonist, these inflammatory biomarkers could be significantly upregulated by LPS-induced ALI.	W146	46-50	sphingosine-1-phosphate receptor 1	Mus musculus	68-73	
29140922-8	2018	The antihyperalgesic effects of fingolimod were prevented or reversed by the S1PR1 antagonist W146 (1 mg/kg daily, i.p.)	W146	94-98	sphingosine-1-phosphate receptor 1	Mus musculus	77-82	
25383272-6	2013	In contrast, pretreatment of (R)-3-amino-4-(3-hexylphenylamino)-4-oxobutyl phosphonic acid (W146), a selective antagonist of S1P1, significantly augments AMD3100-induced KSL-HSPC mobilization into peripheral blood.	W146	92-96	sphingosine-1-phosphate receptor 1	Mus musculus	125-129	
27671228-6	2017	An S1PR1-selective antagonist, W146, blocked the neuroprotective effects of FTY720.	W146	31-35	sphingosine-1-phosphate receptor 1	Mus musculus	3-8	
21798372-0	2011	The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice.	W146	51-55	sphingosine-1-phosphate receptor 1	Mus musculus	4-38	
23723371-9	2013	HDL-induced endothelial cell migration and Akt/eNOS phosphorylation were completely inhibited by the S1P1 antagonist W146 but not by the S1P3 antagonist CAY10444.	W146	117-121	sphingosine-1-phosphate receptor 1	Mus musculus	101-105	
21798372-8	2011	Our study demonstrates that a S1P1 antagonist, W146, induces a significant but transient blood lymphopenia in mice and a parallel increase in CD4+ and CD8+ lymphocytes in lymph nodes.	W146	47-51	sphingosine-1-phosphate receptor 1	Mus musculus	30-34