PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19683931-1 2009 The first sulfoximine-based inhibitor of human asparagine synthetase (ASNS) with nanomolar potency has been shown to suppress proliferation of asparaginase-resistant MOLT-4 cells in the presence of L-asparaginase. sulfoximine 10-21 asparaginase and isoaspartyl peptidase 1 Homo sapiens 198-212 17185229-5 2006 The adenylated sulfoximine has a cytostatic effect on L-asparaginase-resistant MOLT-4 cells cultured in the presence of L-asparaginase, an enzyme that depletes L-asparagine in the growth medium. sulfoximine 15-26 asparaginase and isoaspartyl peptidase 1 Homo sapiens 54-68 17185229-5 2006 The adenylated sulfoximine has a cytostatic effect on L-asparaginase-resistant MOLT-4 cells cultured in the presence of L-asparaginase, an enzyme that depletes L-asparagine in the growth medium. sulfoximine 15-26 asparaginase and isoaspartyl peptidase 1 Homo sapiens 120-134 22951255-0 2012 A sulfoximine-based inhibitor of human asparagine synthetase kills L-asparaginase-resistant leukemia cells. sulfoximine 2-13 asparaginase and isoaspartyl peptidase 1 Homo sapiens 67-81