PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15930289-4 2005 In addition, forced overexpression of CYP2J2, and CYP BM3F87V or addition of epoxyeicosatrienoic acids (EET) in cultured carcinoma cell lines in vitro markedly accelerated proliferation by analyses of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, cell accounts, and cell cycle analysis, and protected carcinoma cells from apoptosis induced by tumor necrosis factor alpha (TNF-alpha) in cultures. EET 104-107 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 38-44 25388680-6 2015 EPHX2 55Arg, CYP2J2*7, CYP2C8*1B, and CYP2C8 g.36785A allele carriers had lower EET and DHET CSF levels. EET 80-83 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 13-19 20412023-1 2010 Human mesenchymal stem cells (MSCs) expressed substantial levels of CYP2J2, a major CYP450 involved in epoxyeicosatrienoic acid (EET) formation. EET 129-132 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 68-74 20194533-1 2010 Cytochrome P450 2J2 oxidizes arachidonic acid to a series of epoxyeicosatrienoic acid (EET) isomers in human tissues. EET 87-90 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 0-19 21656078-5 2012 Inhibition of COX-2 resulted in increased production of LTB(4) and 14-15-DHET/EET, metabolites of 5-LO and CYP2J2, respectively. EET 78-81 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 107-113 18303964-1 2008 UNLABELLED: The cytochrome P450 enzymes CYP2C8, CYP2C9 and CYP2J2 generate 8,9-, 11,12-, and 14,15-epoxyeicosatrienic acid (EET) from arachidonic acid, and these EETs are then hydrolyzed to dihydroxyeicosatrienoic acids (DHET) before excretion into the urine. EET 124-127 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 59-65 33716791-8 2021 The EET-related drug development against cardiac remodeling is also discussed, including the overexpression of CYP2J2, inhibition of sEH, and the analogs of EET. EET 4-7 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 111-117 35078036-2 2022 Cytochrome P450 2J2 (CYP2J2) is a cytochrome P450 epoxygenase in human cardiomyocytes that converts arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acid (EET) regioisomers. EET 168-171 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 0-19 35078036-2 2022 Cytochrome P450 2J2 (CYP2J2) is a cytochrome P450 epoxygenase in human cardiomyocytes that converts arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acid (EET) regioisomers. EET 168-171 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 21-27