PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34865994-16 2022 In conclusion, LLDT-8 played a protective role against ALI and suppressed dendritic cell activation potentially through affecting TLR4 expression and NF-kappaB signaling. 5alpha-Hydroxytriptolide 15-21 nuclear factor kappa B subunit 1 Homo sapiens 150-159 27286958-9 2016 In addition, LLDT-8 suppressed expression of TLR4, degradation of IkappaBalpha and nuclear translocation of NF-kappaB. 5alpha-Hydroxytriptolide 13-19 nuclear factor kappa B subunit 1 Homo sapiens 108-117 27286958-10 2016 CONCLUSION: LLDT-8 exerted anti-inflammatory effects and protected against acute cerebral ischemia/reperfusion injury possibly by acting through the IkappaB/NF-kappaB cascade to suppress microglia-mediated neuroinflammation. 5alpha-Hydroxytriptolide 12-18 nuclear factor kappa B subunit 1 Homo sapiens 157-166