PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22289921-5 2012 The pleckstrin homology domain of wt ITK binds most prominently to phosphatidylinositol monophosphates (PI(3)P, PI(4)P, PI(5)P) and to lesser extend to its double or triple phosphorylated derivates (PIP2, PIP3), interactions which were dramatically reduced in the patient with the ITK(R29H) mutant. 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'D-myo-inositol-3'-phosphate) 104-110 IL2 inducible T cell kinase Homo sapiens 37-40