PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27079728-5	2016	Furthermore, interference of the Abeta-induced interaction of calcineurin with FOXO3 by decoy compounds significantly decreased amyloid-beta protein precursor (AbetaPP) synthesis, reduced the AbetaPP amyloidogenic pathway, resulting in lower Abeta levels, and blocked the expression of pro-inflammatory cytokines TNFalpha and IL-6 in astrocytes.	UNII-042A8N37WH	33-38	interleukin 6	Homo sapiens	326-330	
17446059-6	2007	EGCG significantly inhibited the IL-1beta+Abeta (25-35)-induced IL-6, IL-8, vascular endothelial growth factor (VEGF) and prostaglandin (PG)E(2) production at 24 h (P<.01).	UNII-042A8N37WH	42-47	interleukin 6	Homo sapiens	64-68	
20136701-7	2010	In addition, melatonin significantly reduced the activation of GSK-3beta, the phosphorylation of tau protein, the glial activation and the Abeta-induced increase of TNF-alpha and IL-6 levels.	UNII-042A8N37WH	139-144	interleukin 6	Homo sapiens	179-183	
16371321-8	2005	Freshly dissolved Abeta(1-40) (5-60 microM) resulted in a dose-dependent decrease in cell viability, along with a dose-dependent increase in IL-6 release.	UNII-042A8N37WH	18-23	interleukin 6	Homo sapiens	141-145	
15652404-2	2005	Abeta(1-42) (5 microM) applied for 8 h induced the expression and increased the production of the pro-inflammatory cytokines IL-6, IL-1beta, TNF-alpha, the inducible enzyme COX-2 and chemokine IL-8.	UNII-042A8N37WH	0-5	interleukin 6	Homo sapiens	125-129	
15588680-6	2005	The production of IL-6 and IL-8 was dose-dependently inhibited by pretreatment with ZST (0.01-1 mg/ml) on IL-1beta and Abeta-stimulated U373MG cells.	UNII-042A8N37WH	119-124	interleukin 6	Homo sapiens	18-22