PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15115658-8 2004 Pretreatment with PP2, a specific inhibitor of Src family tyrosine kinase, completely blocked the NHERF2-dependent increase of the phosphorylation of ERK and Akt, suggesting that NHERF2 up-regulates Erk phosphorylation through a Src family kinase-dependent pathway. pp2 18-21 Eph receptor B1 Rattus norvegicus 150-153 17911376-7 2008 In addition, inhibition of Src with its specific inhibitor 4-amino-5-(4-chlorophenyl)-7-(t-butyl) pyrazolo[3,4-d]pyrimidine (PP2) abolishes angiotensin II-, but not EGF-or PDGF-, mediated phosphorylation of ERK in RmuVSMCs, yet it has no effect in TASMCs. pp2 125-128 Eph receptor B1 Rattus norvegicus 207-210 16888778-7 2007 Pretreatment with PP2, a Src inhibitor, significantly suppresses the stretch-induced increases in FAK, paxillin, Src, ERK and caldesmon phosphorylation and myometrial contractility. pp2 18-21 Eph receptor B1 Rattus norvegicus 118-121 15115658-8 2004 Pretreatment with PP2, a specific inhibitor of Src family tyrosine kinase, completely blocked the NHERF2-dependent increase of the phosphorylation of ERK and Akt, suggesting that NHERF2 up-regulates Erk phosphorylation through a Src family kinase-dependent pathway. pp2 18-21 Eph receptor B1 Rattus norvegicus 199-202 35181997-7 2022 Furthermore, ERK phosphorylation is decreased in aortic tissue treated with the Src inhibitor PP2. pp2 94-97 Eph receptor B1 Rattus norvegicus 13-16 11827698-6 2002 H(2)O(2)-induced ERK activation was inhibited not only by PD98059 (10 microM), but also by the non-selective tyrosine kinase inhibitor genistein (3-100 microM), the EGF receptor kinase inhibitor AG1478 (3-300 nM) and the Src family kinase inhibitor PP2 (0.1-10 microM). pp2 249-252 Eph receptor B1 Rattus norvegicus 17-20