PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26759240-6	2016	Furthermore, we show that the p110beta D1067Y mutant was highly activated and induced PIP3 levels at the cell membrane, subsequently promoting the localization and activation of AKT and PDK1 at the membrane and driving PI3K signaling to a level that could withstand treatment with proximal inhibitors.	PIP3	86-90	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	30-38	
25544637-2	2015	This study reveals that, even among these sensitive cancers, the initial efficacy of p110alpha inhibition is mitigated by rapid re-accumulation of the PI3K product PIP3 produced by the p110beta isoform.	PIP3	164-168	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	Homo sapiens	185-193