PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12480812-6	2002	In cardiac fibroblasts with TNF-alpha-induced AT1 receptor upregulation, Ang II-stimulated [3H]proline incorporation and TIMP-1 protein production was approximately 2-fold greater than in nonpretreated fibroblasts.	Tritium	92-94	angiotensin II receptor, type 1a	Rattus norvegicus	46-49	
16962210-2	2006	Angiotensin II enhanced tritium overflow evoked by trains of 100 pulses at 8 Hz, an effect that was attenuated by the AT1-receptor antagonist losartan (0.3-1 microM), at concentrations suggesting the involvement of the AT1B subtype.	Tritium	24-31	angiotensin II receptor, type 1a	Rattus norvegicus	118-121	
15639476-3	2005	Saturation binding studies at AT1 receptors and L-type calcium channels were performed using [3H] Ang II and [3H] PN200110, respectively.	Tritium	94-96	angiotensin II receptor, type 1a	Rattus norvegicus	30-33	
15639476-3	2005	Saturation binding studies at AT1 receptors and L-type calcium channels were performed using [3H] Ang II and [3H] PN200110, respectively.	Tritium	110-112	angiotensin II receptor, type 1a	Rattus norvegicus	30-33	
15501693-10	2004	[3H] Ang II binding at AT1 receptors was unaltered in vascular smooth muscle membranes prepared from thoracic aorta exposed to HG for 2 h compared to NG exposed aortic rings.	Tritium	1-3	angiotensin II receptor, type 1a	Rattus norvegicus	23-26	
8593828-7	1996	Chronic stimulation of [3H]-NE uptake by Ang II persists throughout the duration of Ang II incubation (24 h), is dose dependent, and is also mediated by AT1 receptor subtype.	Tritium	24-26	angiotensin II receptor, type 1a	Rattus norvegicus	153-156	
9736248-5	1998	Ang II increases intracellular inositol 1,4,5-triphosphate (IP3) and [Ca2+]i and stimulates [3H]thymidine incorporation and extracellular matrix (ECM) synthesis via AT1A receptors.	Tritium	93-95	angiotensin II receptor, type 1a	Rattus norvegicus	165-169	
8675248-10	1996	The AT1 antagonist losartan or L-158,809 but not AT2 antagonists blocked [3H]thymidine incorporation by Ang II.	Tritium	74-76	angiotensin II receptor, type 1a	Rattus norvegicus	4-7	
8282003-1	1993	[3H]SR 47436, a selective and potent novel non-peptide antagonist of angiotensin receptors, was used to characterize the cardiac angiotensin AT1 receptors.	Tritium	1-3	angiotensin II receptor, type 1a	Rattus norvegicus	141-144	
8575530-2	1995	This compound potently displaced [3H]angiotensin II from angiotensin AT1 (Ki = 1.4 nM, rat adrenal cortex), but not from angiotensin AT2 (Ki > 1 microM, bovine cerebellar cortex) receptors and did not show affinity for other receptor systems (Ki > 10 microM).	Tritium	34-36	angiotensin II receptor, type 1a	Rattus norvegicus	69-72	
7952881-13	1994	These results confirm that All can stimulate DNA synthesis in VSMC through an AT, receptor.Furthermore, the pharmacological characterization of this AT1 receptor is compatible with the ATlA receptor subtype recently described on cultured mesangial cells since (i) the ATIA/ATIB receptor antagonist losartan is active at nanomolar concentrations, (ii) micromolar concentrations of the AT2/AT1B receptor antagonist PD 123319 are ineffective at antagonizing the AII-induced [3H]-thymidine incorporation and (iii) All is at least 50 times more potent than AIII in stimulating DNA synthesis.	Tritium	472-474	angiotensin II receptor, type 1a	Rattus norvegicus	149-152	
7769798-2	1995	The compound potently displaced [3H]AII from AT1 but not from AT2 receptors in rat adrenal cortex (Ki 3 nM), but did not modify the dissociation rate of the radioligand from the receptors.	Tritium	33-35	angiotensin II receptor, type 1a	Rattus norvegicus	45-48	
7853190-3	1995	GR138950 competed with [3H]-AII for angiotensin AT1 receptors in rat liver membranes (pKi = 9.09).	Tritium	24-26	angiotensin II receptor, type 1a	Rattus norvegicus	48-51	
7952881-8	1994	The stimulatory effect of AII (3 nM) on [3H]-thymidine incorporation in VSMC was antagonized by the non-selective AT1/AT2 receptor antagonist, [Sar1, Ile8]-AII (IC50 = 5.6 nM), by the AT1A/AT1B receptor antagonist, losartan (IC50 = 10.5 nM) and the AT1 receptor antagonist, L-158809 (IC50 = 0.20 nM).	Tritium	41-43	angiotensin II receptor, type 1a	Rattus norvegicus	114-117	
7952881-8	1994	The stimulatory effect of AII (3 nM) on [3H]-thymidine incorporation in VSMC was antagonized by the non-selective AT1/AT2 receptor antagonist, [Sar1, Ile8]-AII (IC50 = 5.6 nM), by the AT1A/AT1B receptor antagonist, losartan (IC50 = 10.5 nM) and the AT1 receptor antagonist, L-158809 (IC50 = 0.20 nM).	Tritium	41-43	angiotensin II receptor, type 1a	Rattus norvegicus	184-188	
7952881-8	1994	The stimulatory effect of AII (3 nM) on [3H]-thymidine incorporation in VSMC was antagonized by the non-selective AT1/AT2 receptor antagonist, [Sar1, Ile8]-AII (IC50 = 5.6 nM), by the AT1A/AT1B receptor antagonist, losartan (IC50 = 10.5 nM) and the AT1 receptor antagonist, L-158809 (IC50 = 0.20 nM).	Tritium	41-43	angiotensin II receptor, type 1a	Rattus norvegicus	184-187	
8206129-6	1994	These properties demonstrate that [3H]A-81988 will be a useful radioligand for studies of angiotensin AT1 receptors in various tissues.	Tritium	35-37	angiotensin II receptor, type 1a	Rattus norvegicus	102-105	
7787253-0	1994	Whole-body autoradiographic study of [3H]-PK 11195 distribution in dunning AT-1 tumour-bearing rats.	Tritium	38-40	angiotensin II receptor, type 1a	Rattus norvegicus	75-79	
8463997-7	1993	COS cells transfected with cDNA encoding human AT1 angiotensin II receptors also displayed high affinity binding site for [3H]SK&F 108566.	Tritium	123-125	angiotensin II receptor, type 1a	Rattus norvegicus	47-50	
8463997-9	1993	These observations indicate that [3H]SK&F 108566 binds to sites which have pharmacological characteristics of angiotensin II AT1 subtype receptors and can be used as a subtype-selective radioligand to characterize AII receptors in various systems.	Tritium	34-36	angiotensin II receptor, type 1a	Rattus norvegicus	129-132	
1480133-0	1992	Characterization of the binding of [3H]L-158,809: a new potent and selective nonpeptide angiotensin II receptor (AT1) antagonist radioligand.	Tritium	36-38	angiotensin II receptor, type 1a	Rattus norvegicus	113-116	
1480133-1	1992	[3H]L-158,809, a new potent and AT1-selective nonpeptide angiotensin II receptor antagonist, bound saturably and reversibly to rat adrenal membranes.	Tritium	1-3	angiotensin II receptor, type 1a	Rattus norvegicus	32-35	
1480133-7	1992	Collectively, the data indicate that [3H]L-158,809 represents a new, potent, nonpeptide, antagonist radioligand suitable for the study of angiotensin II AT1 receptors.	Tritium	38-40	angiotensin II receptor, type 1a	Rattus norvegicus	153-156