PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7541943-1 1995 Recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3) effects on basal, insulin-like growth factor I (IGF-I)-, and follicle-stimulating hormone (FSH)-stimulated progesterone (P4) secretion and [3H]aminoisobutyric acid (AIB) uptake by primary porcine granulosa cells (MDGs) and MDGs that have been passaged once (MDGp1) were assessed. Tritium 215-217 insulin like growth factor binding protein 3 Homo sapiens 18-62 15178549-10 2004 IGFBP-3 also caused IGF-I-independent inhibition of basal [3H]thymidine incorporation. Tritium 59-61 insulin like growth factor binding protein 3 Homo sapiens 0-7 15178549-12 2004 Immunoneutralization of IGFBP-3 increased basal [3H]thymidine incorporation, implying that endogenous IGFBP-3 inhibits proliferation. Tritium 49-51 insulin like growth factor binding protein 3 Homo sapiens 24-31 15178549-12 2004 Immunoneutralization of IGFBP-3 increased basal [3H]thymidine incorporation, implying that endogenous IGFBP-3 inhibits proliferation. Tritium 49-51 insulin like growth factor binding protein 3 Homo sapiens 102-109 7541943-5 1995 However, the IGF-I-stimulated increase in [3H]AIB uptake was completely prevented by concurrent treatment with IGFBP-3. Tritium 43-45 insulin like growth factor binding protein 3 Homo sapiens 111-118 7507320-4 1994 10(-10) M estradiol (E2) significantly stimulated MCF7 proliferation, and co-incubation of estrogen containing cultures with 50nM IGF-BP3 resulted in significant attenuation of the estrogen-stimulated proliferation ([3H]thymidine incorporation: E2, 147 +/- 18% of control; E2 +/- IGF-BP3, 111 +/- 18% of control, p < 0.05). Tritium 217-219 insulin like growth factor binding protein 3 Homo sapiens 130-137 1720092-8 1991 coli or hIGFBP-3CHO potentiated subsequent IGF-I-stimulated [3H]AIB uptake. Tritium 61-63 insulin like growth factor binding protein 3 Homo sapiens 8-16