PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20478302-5	2010	[3H]methotrexate uptake into S2-hOAT3 cells was significantly inhibited by celecoxib in a concentration-dependent manner and the Ki value was 35.3 microM.	Tritium	1-3	solute carrier family 22 member 8	Homo sapiens	32-37	
24036158-3	2013	We studied the interaction of 12 immunosuppressants with OAT1- and OAT3-mediated [(3)H]-methotrexate (MTX) uptake in cells, and adenosine triphosphate-dependent [(3)H]-MTX transport in membrane vesicles isolated from human embryonic kidney 293 cells overexpressing human MRP2 and MRP4.	Tritium	83-86	solute carrier family 22 member 8	Homo sapiens	67-71	
11669456-2	2001	S2 hOAT1 and S2 hOAT3 exhibited a time- and dose-dependent, and a saturable increase in uptake of [3H]-OTA, with apparent Km values of 0.42 microM (hOAT1) and 0.75 microM (hOAT3).	Tritium	99-101	solute carrier family 22 member 8	Homo sapiens	16-21	
15864504-5	2005	When human OAT3 (hOAT3) and hOAT4 were expressed in Xenopus laevis oocytes, only hOAT3 showed [3H]cortisol uptake in excess of that of water-injected control oocytes.	Tritium	95-97	solute carrier family 22 member 8	Homo sapiens	11-15	
15864504-5	2005	When human OAT3 (hOAT3) and hOAT4 were expressed in Xenopus laevis oocytes, only hOAT3 showed [3H]cortisol uptake in excess of that of water-injected control oocytes.	Tritium	95-97	solute carrier family 22 member 8	Homo sapiens	81-86	
11669456-2	2001	S2 hOAT1 and S2 hOAT3 exhibited a time- and dose-dependent, and a saturable increase in uptake of [3H]-OTA, with apparent Km values of 0.42 microM (hOAT1) and 0.75 microM (hOAT3).	Tritium	99-101	solute carrier family 22 member 8	Homo sapiens	172-177	
28630284-5	2017	With OAT3, a dose-dependent inhibition of [3H]ES uptake and a downward shift in [3H]ES equilibrium were observed, indicating that all four drugs bind to OAT3 and may possibly be translocated.	Tritium	43-45	solute carrier family 22 member 8	Homo sapiens	5-9	
29353278-7	2018	The IC50 value of (S)-lansoprazole against hOAT3-mediated transport of [3H]ES (0.61 +- 0.08 micromol/L) was significantly lower than that of (R)-lansoprazole (1.75 +- 0.31 micromol/L).	Tritium	72-74	solute carrier family 22 member 8	Homo sapiens	43-48	
28630284-5	2017	With OAT3, a dose-dependent inhibition of [3H]ES uptake and a downward shift in [3H]ES equilibrium were observed, indicating that all four drugs bind to OAT3 and may possibly be translocated.	Tritium	81-83	solute carrier family 22 member 8	Homo sapiens	5-9	
28630284-5	2017	With OAT3, a dose-dependent inhibition of [3H]ES uptake and a downward shift in [3H]ES equilibrium were observed, indicating that all four drugs bind to OAT3 and may possibly be translocated.	Tritium	81-83	solute carrier family 22 member 8	Homo sapiens	153-157	
28566636-6	2017	In this study, [3H]MTX uptake was observed by using human OAT1 and OAT3-overexpressing HEK293 cells in the presence or absence of NSAIDs-Glu.	Tritium	16-18	solute carrier family 22 member 8	Homo sapiens	67-71