PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33964142-7 2021 Using a biochemical assay for SARM1 NADase we identified a novel series of potent and selective irreversible isothiazole inhibitors of SARM1 enzymatic activity that protected rodent and human axons in vitro. Isothiazole 109-120 sterile alpha and TIR motif containing 1 Homo sapiens 30-35 33964142-7 2021 Using a biochemical assay for SARM1 NADase we identified a novel series of potent and selective irreversible isothiazole inhibitors of SARM1 enzymatic activity that protected rodent and human axons in vitro. Isothiazole 109-120 sterile alpha and TIR motif containing 1 Homo sapiens 135-140