PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22607669-2	2012	This series derived from a pyrazolopyrimidine series previously reported as inhibitors of aurora kinases and CDKs.	1H-pyrazolo[4,3-d]pyrimidine	27-45	cyclin dependent kinase 1	Homo sapiens	109-113	
22326168-2	2012	In addition to targeting these Aurora kinases involved in mitosis, CDK1 has been added as a primary inhibition target in hopes of enhancing the cytotoxicity of our chemotypes harboring the pyrazolopyrimidine core.	1H-pyrazolo[4,3-d]pyrimidine	189-207	cyclin dependent kinase 1	Homo sapiens	67-71