PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15010462-4 2004 Conversely, inhibition of Src family tyrosine kinases by the pyrazolopyrimidine PP2, as in kinase-inactive Hck mutants, significantly reduces IL-6-triggered activation of extracellular signal-regulated kinase and AKT-1, leading to significant reduction of multiple myeloma cell proliferation and survival. 1H-pyrazolo[4,3-d]pyrimidine 61-79 interleukin 6 Homo sapiens 142-146