PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21975240-2	2011	The more reactive conformation is the homocysteine thiolactone (HcyT), product to the nonspecific action of methionyl-tRNA synthetase, which is incorporated into proteins by disulfide bonds (S-homocysteinilation) or amide bonds (N-homocysteinilation) affecting protein structure and function leading to cell toxicity, autoimmune responses and atherogenesis.	Thiolactone	51-62	methionyl-tRNA synthetase 1	Homo sapiens	108-133	
20221875-1	2010	The thioester homocysteine (Hcy)-thiolactone, product of an error-editing reaction in protein biosynthesis, forms when Hcy is mistakenly selected by methionyl-tRNA synthetase.	Thiolactone	33-44	methionyl-tRNA synthetase 1	Homo sapiens	149-174	
11686577-6	2001	A post-translational pathway involves: 1) metabolic conversion of Hcy to thiolactone by methionyl-tRNAsynthetase (MetRS), and 2) acylation of protein lysine residues by Hcy thiolactone.	Thiolactone	73-84	methionyl-tRNA synthetase 1	Homo sapiens	114-119	
20510245-2	2010	Homocysteine thiolactone is a cyclic thioester, most of which is produced by an error-editing function of methionyl-tRNA synthetase, causing in vivo post-translational protein modifications by reacting with the epsilon-amino group of lysine residues.	Thiolactone	13-24	methionyl-tRNA synthetase 1	Homo sapiens	106-131