PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 185-254 TNF receptor superfamily member 10b Homo sapiens 22-38 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 185-254 TNF receptor superfamily member 10b Homo sapiens 40-43 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 185-254 TNF receptor superfamily member 10b Homo sapiens 92-95 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 96-100 TNF receptor superfamily member 10b Homo sapiens 22-38 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 96-100 TNF receptor superfamily member 10b Homo sapiens 40-43 33385372-1 2021 In the present study, Death receptor-5 (DR5) antibody conjugated solid lipid nanoparticles (DR5-DAPT-SLNs) has been formulated for effective intracellular of gamma-secretase inhibitor, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester (DAPT) to cancer cells. dapt 96-100 TNF receptor superfamily member 10b Homo sapiens 92-95 33385372-6 2021 DR5-DAPT-SLNs have higher cytotoxicity in MDA-MB231 cells compared to DAPT-SLNs (non-targeted) and the bulk drug. dapt 4-8 TNF receptor superfamily member 10b Homo sapiens 0-3 33385372-8 2021 The above results, therefore, demonstrate DR5 mediated uptake is responsible for improved cytotoxicity of DAPT. dapt 106-110 TNF receptor superfamily member 10b Homo sapiens 42-45 33385372-9 2021 In the in vivo anticancer study, DR5-DAPT-SLNs show greater tumor regression when compared to DAPT-SLNs and the bulk drug. dapt 37-41 TNF receptor superfamily member 10b Homo sapiens 33-36 33385372-10 2021 In conclusion, the results of the present study demonstrate that the DR5-DAPT-SLNs selectively target cancer cells and potentiate the anticancer efficacy of DAPT against TNBC cells. dapt 73-77 TNF receptor superfamily member 10b Homo sapiens 69-72 33385372-10 2021 In conclusion, the results of the present study demonstrate that the DR5-DAPT-SLNs selectively target cancer cells and potentiate the anticancer efficacy of DAPT against TNBC cells. dapt 157-161 TNF receptor superfamily member 10b Homo sapiens 69-72