PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34245840-2	2021	Here, we present a novel target, a truncated form of neogenin that is associated with seizure-induced hippocampal necroptosis, and novel use of the gamma-secretase inhibitor N-(N-(3,5-Difluorophenacetyl)-L-alanyl)-S-phenylglycine t-butyl ester (DAPT) as a pharmacological regulator of neogenin truncation.	dapt	245-249	neogenin	Mus musculus	285-293	
34245840-6	2021	Notably, treatment with DAPT prevented neogenin truncation and protected cultured neurons from N-methyl-D-aspartate (NMDA)-induced death.	dapt	24-28	neogenin	Mus musculus	39-47	
34245840-7	2021	These data suggest that seizure-induced hippocampal necroptosis is associated with the generation of truncated neogenin, and that prevention of this by DAPT treatment can protect against NMDA-induced excitotoxicity.	dapt	152-156	neogenin	Mus musculus	111-119