PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29417442-13	2018	Moreover, augmented caspase-3 up-regulation and bcl-2 down-regulation were found following combined application of DAPT and ATRA.	dapt	115-119	BCL2 apoptosis regulator	Homo sapiens	48-53	
28400072-8	2017	Compared with the control group, the mRNA abundances of HES1, MYC, BAX, BCL2 and CYP19A1 in DAPT-treated groups was lower (P<0.05), respectively; whereas, the expression of CCND2, CDKN1A and TP53 mRNA showed no remarkable difference compared with control group.	dapt	92-96	BCL2 apoptosis regulator	Homo sapiens	72-76	
28487945-9	2017	Inhibition of the Notch pathway via DAPT increased Bcl-2 expression, decreased Bax and cleaved caspase-3 levels and prevented HKC cell apoptosis.	dapt	36-40	BCL2 apoptosis regulator	Homo sapiens	51-56	
29571073-14	2018	Conversely, treatment with DAPT alone only increased expression of BAX and P53 (P < .05), suggesting that the reduction of Bcl-2 expression may play an important role in the synergetic antitumor and proapoptosis effects of the combined treatment.	dapt	27-31	BCL2 apoptosis regulator	Homo sapiens	126-131