PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8843902-12 1996 The inhibitory effect of AngII was abolished completely by losartan (0.1 microM), a specific antagonist of the AT1 receptor-subtype of AngII, and by nordihydroguaiaretic acid (50 microM), which at this concentration inhibits the lipoxygenase and cytochrome P-450-dependent pathways of arachidonic acid metabolism. Masoprocol 149-174 angiotensinogen Rattus norvegicus 25-30 18475674-3 1995 In the heart, the nonselective lipoxygenase inhibitor nordihydroguaiaretic acid (NDGA, 1 muM) markedly suppressed the angiotensin II-induced decreases in coronary flow. Masoprocol 54-79 angiotensinogen Rattus norvegicus 118-132 18475674-3 1995 In the heart, the nonselective lipoxygenase inhibitor nordihydroguaiaretic acid (NDGA, 1 muM) markedly suppressed the angiotensin II-induced decreases in coronary flow. Masoprocol 81-85 angiotensinogen Rattus norvegicus 118-132 18475674-4 1995 NDGA (10 muM) inhibited both angiotensin II- and methoxamine- (reference drug) induced contractions in aortic rings with (in the presence of L-NAME) and without endothelium. Masoprocol 0-4 angiotensinogen Rattus norvegicus 29-43 2855591-6 1988 Separate experiments showed that inhibitors of arachidonic acid release and metabolism (bromophenacyl bromide, nordihydroguaiaretic acid, caffeic acid or esculetin) blocked corticosterone production in fasciculata cells stimulated with ACTH, suggesting that arachidonic acid could be the common intermediate in the actions of AII and ACTH on steroid synthesis. Masoprocol 111-136 angiotensinogen Rattus norvegicus 326-329 6871537-3 1983 3 Nordihydroguaiaretic acid, a lipoxygenase inhibitor, totally abolished the uterine response to either oxytocin or angiotensin II. Masoprocol 2-27 angiotensinogen Rattus norvegicus 116-130