PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1596675-18	1992	In contrast, NDGA (10 microM) inhibited ET-1- induced contractions (4.0 fold increase in mean EC50, P < 0.001, n = 5).	Masoprocol	13-17	endothelin 1	Rattus norvegicus	40-44	
1383617-5	1992	The ET-1-induced potentiation of the response to serotonin was prevented by nordihydroguaiaretic acid (3 x 10(-6) M), quinacrine (10(-6) M), and AA861 (10(-6) M), but not by indomethacin (10(-7) M) and baicalein (10(-6) M).	Masoprocol	76-101	endothelin 1	Rattus norvegicus	4-8	
8004399-0	1994	Inhibitory effects of nordihydroguaiaretic acid on ETA-receptor-mediated contractions to endothelin-1 in rat trachea.	Masoprocol	22-47	endothelin 1	Rattus norvegicus	89-101	
8004399-2	1994	It has been shown previously that nordihydroguaiaretic acid (NDGA) inhibits endothelin-1 (ET-1)-induced contractions in rat isolated tracheal smooth muscle.	Masoprocol	34-59	endothelin 1	Rattus norvegicus	76-88	
8004399-2	1994	It has been shown previously that nordihydroguaiaretic acid (NDGA) inhibits endothelin-1 (ET-1)-induced contractions in rat isolated tracheal smooth muscle.	Masoprocol	34-59	endothelin 1	Rattus norvegicus	90-94	
8004399-2	1994	It has been shown previously that nordihydroguaiaretic acid (NDGA) inhibits endothelin-1 (ET-1)-induced contractions in rat isolated tracheal smooth muscle.	Masoprocol	61-65	endothelin 1	Rattus norvegicus	76-88	
8004399-2	1994	It has been shown previously that nordihydroguaiaretic acid (NDGA) inhibits endothelin-1 (ET-1)-induced contractions in rat isolated tracheal smooth muscle.	Masoprocol	61-65	endothelin 1	Rattus norvegicus	90-94	
8004399-5	1994	NDGA inhibited contractions induced by each of the isoforms of ET (ET-1, ET-2 and ET-3) but not those induced by the ETB receptor-selective agonist, sarafotoxin S6c, the cholinoceptor agonist, carbachol or the depolarizing spasmogen, KCl.	Masoprocol	0-4	endothelin 1	Rattus norvegicus	67-71	
8004399-9	1994	NDGA inhibited the ETA receptor-mediated, intracellular Ca(2+)-dependent contractions induced by 100 nM ET-1 in Ca(2+)-free solution (by 75%, P < 0.01).	Masoprocol	0-4	endothelin 1	Rattus norvegicus	104-108	
8004399-12	1994	Like NDGA, the sarcoplasmic reticulum Ca(2+)-ATPase inhibitors cyclopiazonic acid and thapsigargin inhibited contractions to ET-1, but not carbachol or KCl.	Masoprocol	5-9	endothelin 1	Rattus norvegicus	125-129	
8004399-16	1994	However, in the presence of NDGA or the ETA receptor antagonist, BQ123, ET-1-induced contractions resembled the transient contractions induced by sarafotoxin S6c.	Masoprocol	28-32	endothelin 1	Rattus norvegicus	72-76	
8004399-19	1994	In summary, NDGA selectively inhibited ET-1-induced contractions in rat tracheal smooth muscle via a lipoxygenase-independent mechanism involving inhibition of the ETA but not the ETB, receptor effector system.	Masoprocol	12-16	endothelin 1	Rattus norvegicus	39-43	
8004399-21	1994	However, NDGA inhibited the intracellular Ca2+-dependent component of ET-1-induced contraction, possibly by inhibiting mobilisation of intracellular Ca2+.	Masoprocol	9-13	endothelin 1	Rattus norvegicus	70-74