PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25280745-7 2014 The resulting strain overexpressing LEU2 and LEU4 (D578Y) , a feedback inhibition-insensitive mutant of LEU4, showed a 34-fold increase in 3-methyl-1-butanol synthesis compared with CEN.PK2-1C control strain, producing 765.7 mg/L 3-methyl-1-butanol. Glutaryl-7-aca 182-185 2-isopropylmalate synthase LEU4 Saccharomyces cerevisiae S288C 45-49 25280745-7 2014 The resulting strain overexpressing LEU2 and LEU4 (D578Y) , a feedback inhibition-insensitive mutant of LEU4, showed a 34-fold increase in 3-methyl-1-butanol synthesis compared with CEN.PK2-1C control strain, producing 765.7 mg/L 3-methyl-1-butanol. Glutaryl-7-aca 182-185 2-isopropylmalate synthase LEU4 Saccharomyces cerevisiae S288C 104-108