PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15474300-1 2004 Lecithin:retinol acyltransferase (LRAT) catalyzes the synthesis of retinyl esters in many tissues and is crucial for the transport and intracellular storage of vitamin A. retinyl esters 67-81 lecithin retinol acyltransferase Homo sapiens 0-32 27815220-6 2017 Quiescent LRAT-/- HSCs retain the capacity to synthesize retinyl esters and to store neutral lipids in lipid droplets ex vivo. retinyl esters 57-71 lecithin retinol acyltransferase Homo sapiens 10-14 34836244-5 2021 CRBP2 bound retinol is then converted into retinyl esters (REs) by the enzyme lecithin retinol acyltransferase (LRAT) in the endoplasmic reticulum, which is then packaged into chylomicrons and sent into the bloodstream for storage in hepatic stellate cells in the liver or for functional use in peripheral tissues such as the retina. retinyl esters 43-57 lecithin retinol acyltransferase Homo sapiens 78-110 34836244-5 2021 CRBP2 bound retinol is then converted into retinyl esters (REs) by the enzyme lecithin retinol acyltransferase (LRAT) in the endoplasmic reticulum, which is then packaged into chylomicrons and sent into the bloodstream for storage in hepatic stellate cells in the liver or for functional use in peripheral tissues such as the retina. retinyl esters 43-57 lecithin retinol acyltransferase Homo sapiens 112-116 17016651-2 2006 We have shown that expression of the enzyme lecithin:retinol acyltransferase (LRAT), which converts retinol to retinyl esters, is reduced in several human carcinomas as compared with adjacent normal tissue from the same organs. retinyl esters 111-125 lecithin retinol acyltransferase Homo sapiens 44-76 17016651-2 2006 We have shown that expression of the enzyme lecithin:retinol acyltransferase (LRAT), which converts retinol to retinyl esters, is reduced in several human carcinomas as compared with adjacent normal tissue from the same organs. retinyl esters 111-125 lecithin retinol acyltransferase Homo sapiens 78-82 16011460-2 2005 Dietary retinyl esters are hydrolyzed in the intestine by the pancreatic enzyme, pancreatic triglyceride lipase, and intestinal brush border enzyme, phospholipase B. Unesterified retinol taken up by the enterocyte is complexed with cellular retinol-binding protein type 2 and the complex serves as a substrate for reesterification of the retinol by the enzyme lecithin:retinol acyltransferase (LRAT). retinyl esters 8-22 lecithin retinol acyltransferase Homo sapiens 360-392 15474300-1 2004 Lecithin:retinol acyltransferase (LRAT) catalyzes the synthesis of retinyl esters in many tissues and is crucial for the transport and intracellular storage of vitamin A. retinyl esters 67-81 lecithin retinol acyltransferase Homo sapiens 34-38 12009892-1 2002 Membrane-bound lecithin retinol acyltransferase (LRAT), an essential enzyme in vitamin A processing, catalyzes the formation of retinyl esters from vitamin A and lecithin. retinyl esters 128-142 lecithin retinol acyltransferase Homo sapiens 15-47 15161698-2 2004 We have shown that expression of the enzyme lecithin:ROL acyltransferase (LRAT), which converts ROL to retinyl esters, is reduced in several human cancers. retinyl esters 103-117 lecithin retinol acyltransferase Homo sapiens 44-72 15161698-2 2004 We have shown that expression of the enzyme lecithin:ROL acyltransferase (LRAT), which converts ROL to retinyl esters, is reduced in several human cancers. retinyl esters 103-117 lecithin retinol acyltransferase Homo sapiens 74-78 12009892-1 2002 Membrane-bound lecithin retinol acyltransferase (LRAT), an essential enzyme in vitamin A processing, catalyzes the formation of retinyl esters from vitamin A and lecithin. retinyl esters 128-142 lecithin retinol acyltransferase Homo sapiens 49-53 9920938-1 1999 The enzyme responsible for conversion of all-trans-retinol into retinyl esters, the lecithin retinol acyltransferase (LRAT) has been characterized at the molecular level. retinyl esters 64-78 lecithin retinol acyltransferase Homo sapiens 84-116 9920938-1 1999 The enzyme responsible for conversion of all-trans-retinol into retinyl esters, the lecithin retinol acyltransferase (LRAT) has been characterized at the molecular level. retinyl esters 64-78 lecithin retinol acyltransferase Homo sapiens 118-122 8663081-7 1996 This reduction in retinoic acid synthesis resulted from sequestration of retinol as retinyl esters, since inhibition of LRAT restored retinoic acid synthesis to control levels. retinyl esters 84-98 lecithin retinol acyltransferase Homo sapiens 120-124 11912136-1 2002 Recent studies from our laboratory have indicated that the metabolism of vitamin A (retinol) to retinyl esters, carried out primarily by the enzyme lecithin:retinol acyltransferase (LRAT), is greatly reduced in human carcinoma cell lines of the oral cavity, skin, breast, and kidney as compared with their normal epithelial counterparts. retinyl esters 96-110 lecithin retinol acyltransferase Homo sapiens 148-180 11912136-1 2002 Recent studies from our laboratory have indicated that the metabolism of vitamin A (retinol) to retinyl esters, carried out primarily by the enzyme lecithin:retinol acyltransferase (LRAT), is greatly reduced in human carcinoma cell lines of the oral cavity, skin, breast, and kidney as compared with their normal epithelial counterparts. retinyl esters 96-110 lecithin retinol acyltransferase Homo sapiens 182-186 11231005-1 2001 Lecithin retinol acyl transferase (LRAT) is a novel membrane bound enzyme that catalyzes the formation of retinyl esters from vitamin A and lecithin. retinyl esters 106-120 lecithin retinol acyltransferase Homo sapiens 0-33 11231005-1 2001 Lecithin retinol acyl transferase (LRAT) is a novel membrane bound enzyme that catalyzes the formation of retinyl esters from vitamin A and lecithin. retinyl esters 106-120 lecithin retinol acyltransferase Homo sapiens 35-39