PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25974161-1	2015	Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment epithelium (RPE).	retinyl esters	0-14	retinal pigment epithelium 65	Mus musculus	111-116	
16223604-3	2006	A naturally occurring rodent model of LCA with a recessive nonsense Rpe65 mutation, the rd12 mouse, displays a profoundly diminished rod electroretinogram (ERG), an absence of 11-cis-retinaldehyde and rhodopsin, an overaccumulation of retinyl esters in retinal pigmented epithelial (RPE) cells, and photoreceptor degeneration.	retinyl esters	235-249	retinal pigment epithelium 65	Mus musculus	68-73	
17251447-8	2007	Ablation of RPE65 in Nrl(-/-) and Rho(-/-) mice led to the absence of 11-cis retinal, but increased the total retinoid content, with retinyl esters representing the most abundant retinoid species.	retinyl esters	133-147	retinal pigment epithelium 65	Mus musculus	12-17	
15722110-9	2005	Mice with a mutation in the Rpe65 gene contain substantial levels of retinol and retinyl esters in the RPE, but little if any retinaldehydes in either the RPE or retina.	retinyl esters	81-95	retinal pigment epithelium 65	Mus musculus	28-33	
14532273-12	2004	These observations suggest that Rpe65 presents retinyl esters as substrate to the isomerase for synthesis of visual chromophore.	retinyl esters	47-61	retinal pigment epithelium 65	Mus musculus	32-37