PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3593228-2	1987	In an effort to elucidate the mechanism of calmodulin regulation of muscle contraction, we investigated the interaction between calmodulin and troponin components in the presence of Ca2+ or Sr2+ by the use of ultracentrifugation methods and polyacrylamide-gel electrophoresis.	strontium cation	190-194	calmodulin 1	Homo sapiens	128-138	
3593228-9	1987	Sr2+-induced exposure of the hydrophobic region enables calmodulin to bind to troponin I, as is the case with Ca2+.	strontium cation	0-4	calmodulin 1	Homo sapiens	56-66	
3593228-4	1987	When troponin T was absent, calmodulin bound to troponin I and dissociated it from the tropomyosin-actin complex in the presence of Ca2+ or Sr2+.	strontium cation	140-144	calmodulin 1	Homo sapiens	28-38	
3593228-7	1987	Calmodulin migrated more slowly in the presence of Sr2+ than it did in the presence of EGTA but faster than it did in the presence of Ca2+ on polyacrylamide-gel electrophoresis under non-denaturing conditions.	strontium cation	51-55	calmodulin 1	Homo sapiens	0-10	
19297189-10	2009	The order of affinity for apo CaM is Ca(2+) >> Sr(2+) approximately Mg(2+) > Pb(2+) approximately Cd(2+).	strontium cation	53-59	calmodulin 1	Homo sapiens	30-33	
6314931-3	1983	Calmodulin dependent phosphodiesterase was activated with Pb2+, Ca2+, Sr2+, Ba2+, and Cd2+ (EC50 about 0.8 microM).	strontium cation	70-74	calmodulin 1	Homo sapiens	0-10	
6314931-10	1983	Calmodulin binding to brain membranes was enhanced with concentrations below 10(-4)M in the following order: Pb2+ greater than or equal to Ca2+ approximately Sr2+ greater than Cd2+ greater than Mn2+ greater than Ba2+.	strontium cation	158-162	calmodulin 1	Homo sapiens	0-10	
6314931-13	1983	In the flow-dialysis, other ions competed with 45Ca2+ binding to calmodulin in the following order: Pb2+ approximately Ca2+ greater than Mn2+, Ba2+, Cd2+, Sr2+.	strontium cation	155-159	calmodulin 1	Homo sapiens	65-75	
9850564-9	1998	Moreover, our data suggest that the toxicity of Pb(2+)--which, like Sr2+, binds with an equal and high affinity to all four sites--may be related to its capacity to tightly bind and improperly activate calmodulin.	strontium cation	68-72	calmodulin 1	Homo sapiens	202-212	
17661504-4	2007	We study CaM complexes with the physiologically important ions of calcium (Ca2+) and magnesium (Mg2+) and also with two other ions, strontium (Sr2+) and lanthanum (La3+).	strontium cation	143-147	calmodulin 1	Homo sapiens	9-12