PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33440488-10 2017 The binding of bivalent ions (such as Ni2+) enhances the thermodynamic stability of the host domain and results in the shift of the conformational equilibrium between the two mutually exclusive conformations of the MEP. Nickel(2+) 38-42 neurolysin Homo sapiens 215-218