PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27717596-6 2016 MYO is the precursor of inositol triphosphate, a second messenger that regulates thyroid-stimulating hormone (TSH) and FSH as well as insulin. Inositol triphosphate 24-45 insulin Homo sapiens 134-141 2698762-3 1989 In the early stage of insulin secretion in particular the intracellular compartment is the source of calcium; from there the ion is released due to the action of inositol triphosphate (IP3) activated by phospholipase C. Calcium of the extracellular compartment is mobilized also in the early secretory stage by opening of the depolarization-dependent calcium channels, it plays, however, a more important part during the second stage. Inositol triphosphate 162-183 insulin Homo sapiens 22-29 25010620-3 2014 Myo-inositol is the precursor of inositol triphosphate, a second messenger regulating many hormones such as TSH, FSH and insulin. Inositol triphosphate 33-54 insulin Homo sapiens 121-128